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The New Panacea in Metabolomics, Proteomics and Genomics -
Electrochemistry / MS
M. Eysberg, J. Purkerson, Antec (USA), Palm Bay, FL, USA
Combining electrochemistry (EC) with Mass Spectrometry (MS) has
shown great potential for the investigation of drug metabolism.
Recently, the use of EC/MS has been extended towards new
applications such as:
- fast synthesis of metabolites (µ-preparative)
- rapid risk assessments of drug-protein binding
- signal enhancement in MS
- electrochemical cleavage of proteins/peptides
All these applications illustrate the tremendous power and
broad applicability of electrochemistry as a promising tool to
mimic natures Redox reactions, including oxidative damage of
DNA, protein stress, lipid oxidation, etc.
Some of these applications will be discussed in more details
during this seminar.
Date: Tuesday, March 23, 2010
Time: 12:00 pm – 12:50 pm
Room nr. 302
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